MyBioSource.com's CEACAM20 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The CEACAM20 Antibody was generated using CEACAM20 as the antigen and it reacts with Human, and Mouse.
Description
Function: Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response.
Subunit Structure: Interacts (via extracellular domain) with PTPRH (via extracellular domain); the interaction dephosphorylates CEACAM20. Interacts (phosphorylated form) with SYK (via SH2 domains); the interaction further enhances CEACAM20 phosphorylation.
Post-translational Modifications: Phosphorylated on tyrosine residues by SYK, SRC and FYN in vitro.
Similarity: Belongs to the immunoglobulin superfamily. CEA family